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Eurycomanone

Cat. No.:YN483219

  • CAS No. :84633-29-4

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Eurycomanone
      CAS No.: 84633-29-4
      Chemical Name: (1β,11β,12α,15β)-11,20-epoxy-1,11,12,14,15-pentahydroxy-picrasa-3,13(21)-diene-2,16-dione
      Synonyms:Pasakbumin A
      分子量:408.40
      分子式:C₂₀H₂₄O₉
      SMILES:O[C@@]1([C@H]2O)[C@@]34[C@@]([C@](OC4)(O)[C@H](O)C1=C)([H])[C@]([C@@](C(C)=CC5=O)([H])C[C@@]3([H])OC2=O)([C@@H]5O)C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Eurycomanone 可通过抑制雌激素生成过程中磷酸二酯酶和芳香酶的活性来促进精子生成。
      IC50和靶点:
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    • Darise, M., Kohda, H., Mizutani, K., et al.Eurycomanone and eurycomanol, quassinoids from the roots of Eurycoma longifoliaPhytochemistry21(8),2091-2093(1982)

      Kuo, P.-C., Damu, A.G., Lee, K.-H., et al.Cytotoxic and antimalarial constituents from the roots of Eurycoma longifoliaBioorg. Med. Chem.12(3),537-544(2004)

      Lahrita, L., Hirosawa, R., Kato, E., et al.Isolation and lipolytic activity of eurycomanone and its epoxy derivative from Eurycoma longifoliaBioorg. Med. Chem.25(17),4829-4834(2017)

      Zakaria, Y., Rahmat, A., Pihie, A.H.L., et al.Eurycomanone induce apoptosis in HepG2 cells via up-regulation of p53Cancer Cell Int.9,(2009)

      Low, B.-S., Choi, S.-B., Wahab, H.A., et al.Eurycomanone, the major quassinoid in Eurycoma longifolia root extract increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesisJ. Ethnopharmacol.149(1),201-207(2013)

      Tada, H., Yasuda, F., Otani, K., et al.New antiulcer quassinoids from Eurycoma longifoliaEur. J. Med. Chem.26(3),345-349(1991)

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