Rosmanol
Cat. No.：YN483220
| 产品名称: | Rosmanol |
| CAS No.: | 80225-53-2 |
| Chemical Name: | (4aR,9S,10S,10aS)-1,3,4,9,10,10a-hexahydro-5,6,9-trihydroxy-1,1-dimethyl-7-(1-methylethyl)-2H-10,4a-(epoxymethano)phenanthren-12-one |
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| 分子量: | 346.42 |
| 分子式: | C₂₀H₂₆O₅ |
| SMILES: | O=C1O[C@]2([H])[C@@H](O)C3=C(C(O)=C(O)C(C(C)C)=C3)[C@@]41CCCC(C)(C)[C@]24[H] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Rosmanol能够抑制低密度脂蛋白的氧化，显著抑制脂多糖诱导的 INOS、COX-2 的表达，并具有抗炎活性。 |
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Lai, C.-S., Lee, J.H., Ho, C.-T., et al.Rosmanol potently inhibits lipopolysaccharide-induced iNOS and COX-2 expression through downregulating MAPK, NF-κB, STAT3 and C/EBP signaling pathwaysJ. Agric. Food Chem.57(22),10990-10998(2009)
Etsassala, N.G.E.R., Badmus, J.A., Marnewick, J.L., et al.Alpha-glucosidase and alpha-amylase inhibitory activities, molecular docking, and antioxidant capacities of Salvia aurita constituentsAntioxidants9(11),1149(2020)
Cheng, A.-C., Lee, M.-F., Tsai, M.-L., et al.Rosmanol potently induces apoptosis through both the mitochondrial apoptotic pathway and death receptor pathway in human colon adenocarcinoma COLO 205 cellsFood Chem. Toxicol.49(2),485-493(2011)
Abdelhalim, A., Karim, N., Chebib, M., et al.Antidepressant, anxiolytic and antinociceptive activities of constituents from Rosmarinus officinalisJ. Pharm. Pharm. Sci.18(4),448-459(2015)
