Saponarin
Cat. No.：YN483247
CAS No. ：20310-89-8
| 产品名称: | Saponarin |
| CAS No.: | 20310-89-8 |
| Chemical Name: | 6-β-D-glucopyranosyl-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| Synonyms: | 皂草甙 |
| 分子量: | 594.52 |
| 分子式: | C₂₇H₃₀O₁₅ |
| SMILES: | O=C1C=C(C2=CC=C(O)C=C2)OC3=CC(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)=C([C@H]5[C@@H]([C@H]([C@@H]([C@@H](CO)O5)O)O)O)C(O)=C13 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Saponarin 是一种从Gypsophila trichotoma中分离出的天然的黄酮类化合物，具有抗氧化、抗炎和保护肝脏的作用。Saponarin 以钙依赖的方式激活AMPK，从而调节糖异生和葡萄糖摄取。 |
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Kamiyama, M., and Shibamoto, T.Flavonoids with potent antioxidant activity found in young green barley leavesJ. Agric. Food Chem.60(25),6260-6267(2012)
Seo, W.-D., Lee, J.H., Jia, Y., et al.Saponarin activates AMPK in a calcium-dependent manner and suppresses gluconeogenesis and increases glucose uptake via phosphorylation of CRTC2 and HDAC5Bioorg. Med. Chem. Lett.25(22),5237-5242(2015)
Min, S.-Y., Park, C.-H., Yu, H.-W., et al.Anti-inflammatory and anti-allergic effects of saponarin and its impact on signaling pathways of RAW 264.7, RBL-2H3, and HaCaT cellsInt. J. Mol. Sci.22(16),8431(2021)
Vitcheva, V., Simeonova, R., Krasteva, I., et al.Hepatoprotective effects of saponarin, isolated from Gypsophila trichotoma Wend. on cocaine-induced oxidative stress in ratsRedox Rep.16(2),56-61(2011)
