Byakangelicin
Cat. No.:YN483275
CAS No. :482-25-7
产品名称: | Byakangelicin |
CAS No.: | 482-25-7 |
Chemical Name: | 9-[(2R)-2,3-dihydroxy-3-methylbutoxy]-4-methoxy-7H-furo[3,2-g][1]benzopyran-7-one |
Synonyms: | 白当归素 |
分子量: | 334.32 |
分子式: | C₁₇H₁₈O₇ |
SMILES: | CC(C)(O)[C@H](O)COC1=C(OC=C2)C2=C(OC)C(C=C3)=C1OC3=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Byakangelicin 是一种在当归 (Angelica gigas) 根中发现的活性化合物,可以作为调节剂,改善各种活性化合物 (Umb,Cur 和 Dox) 的脑积累,增强研究效果。Byakangelicin 增加所有PXR靶基因 (如MDR1) 的表达,并诱导广泛的药物-药物相互作用。Byakangelicin 可以抑制性激素的作用,它可能会增加内源激素的分解代谢。 |
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Shin, K.H., Chung, M.S., and Cho, T.S.Effects of furanocoumarins from Angelica dahurica on aldose reductase and galactosemic cataract formation in ratsArch. Pharm. Res.17(5),331-336(1994)
Ban, H.S., Lim, S.S., Suzuki, K., et al.Inhibitory effects of furanocoumarins isolated from the roots of Angelica dahurica on prostaglandin E2 productionPlanta Med.69(5),408-412(2003)
Zhang, T., He, L., Yang, W., et al.Byakangelicin inhibits IL-1β-induced mouse chondrocyte inflammation in vitro and ameliorates murine osteoarthritis in vivoInt. Immunopharmacol.85,106605(2020)