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Gartanin

Cat. No.:YN483280

  • CAS No. :33390-42-0

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    • 参考文献
    • 产品名称: Gartanin
      CAS No.: 33390-42-0
      Chemical Name: 1,3,5,8-tetrahydroxy-2,4-bis(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
      Synonyms:1,3,5,8-四羟基-2,4-双(3-甲基-2-丁烯基)-9H-氧杂蒽-9-酮,藤黄苷
      分子量:396.43
      分子式:C₂₃H₂₄O₆
      SMILES:O=C1C2=C(OC3=C(O)C=CC(O)=C13)C(C/C=C(C)\C)=C(O)C(C/C=C(C)/C)=C2O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Gartanin 是山竹果中的天然黄酮,具有抗氧化、抗炎、抗真菌、神经保护和抗肿瘤作用。在人脑胶质瘤细胞中,Gartanin 诱导细胞周期阻滞和自噬,抑制其迁移。
      IC50和靶点:
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    • Liu, Z., Antalek, M., Nguyen, L., et al.The effect of gartanin, a naturally occurring xanthone in mangosteen juice, on the mTOR pathway, autophagy, apoptosis, and the growth of human urinary bladder cancer cell linesNutr. Cancer65 Suppl. 1 (0 1),68-77(2013)

      Pham, V., Rendon, R., Le, V.X., et al.Gartanin is a novel NEDDylation inhibitor for induction of Skp2 degradation, FBXW2 expression, and autophagyMol. Carcinog.59(2),193-201(2020)

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