2-O-Acetyl-20-hydroxyecdysone
Cat. No.：YN483326
| 产品名称: | 2-O-Acetyl-20-hydroxyecdysone |
| CAS No.: | 19536-25-5 |
| Chemical Name: | (2β,3β,5β,22R)-2-(acetyloxy)-3,14,20,22,25-pentahydroxy-cholest-7-en-6-one |
| Synonyms: | 20-Hydroxyeedysone 2-acetate |
| 分子量: | 522.67 |
| 分子式: | C₂₉H₄₆O₈ |
| SMILES: | C[C@@]12[C@@](C(C=C3[C@]2([H])CC[C@@]4(C)[C@@]3(O)CC[C@]4([H])[C@](O)(C)[C@H](O)CCC(O)(C)C)=O)([H])C[C@@H](O)[C@@H](OC(C)=O)C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 2-O-Acetyl-20-hydroxyecdysone，是存在于昆虫和陆生植物中的一种蜕皮激素， 抑制 amyloid-β42诱导的细胞毒性。2-O-Acetyl-20-hydroxyecdysone 能够通过促进纤维发生减少Aβ寡聚物的形成，将 Aβ 寡聚物转变为低毒性纤维。 |
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Shirshova, T.I., Politova, N.K., Burtseva, S.A., et al.Antimicrobial activity of natural ecdysteroids from Serratula coronata L. and their acyl derivativesPharm. Chem. J.40(5),268–271(2006)
Yang, S.-G., Zhang, X., Sun, X.-S., et al.Diverse ecdysterones show different effects on amyloid-β42 aggregation but all uniformly inhibit amyloid-β42-induced cytotoxicityJ. Alzheimers. Dis.22(1),107-117(2010)
