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Altertoxin I

Cat. No.:YN483359

  • CAS No. :56258-32-3

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    • 生物活性
    • 参考文献
    • 产品名称: Altertoxin I
      CAS No.: 56258-32-3
      Chemical Name: (1S,12aR,12bS)-1,2,11,12,12a,12b-hexahydro-1,4,9,12a-tetrahydroxy-3,10-perylenedione
      Synonyms:Dihydroalterperylenol
      分子量:352.34
      分子式:C₂₀H₁₆O₆
      SMILES:O=C(C1=C2C3=CC=C1O)CC[C@]2([C@@]([H])(C4=C3C=CC(O)=C45)[C@H](CC5=O)O)O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Altertoxin I (Dihydroalterperylenol) 是由Alternaria alternata产生的一种醌类真菌毒素,具有诱变作用和细胞毒性,能较弱地干扰代谢通讯。
      IC50和靶点:
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      In Vivo:
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    • Jarolim, K., Del Favero, G., Ellmer, D., et al.Dual effectiveness of Alternaria but not Fusarium mycotoxins against human topoisomerase II and bacterial gyraseArch. Toxicol.91(4),2007-2016(2016)

      Stack, M.E., and Prival, M.J.Mutagenicity of the Alternaria metabolites altertoxins I, II, and IIIAppl. Environ. Microbiol.52(4),718-722(1986)

      Bashyal, B.P., Wellensiek, B.P., Ramakrishnan, R., et al.Altertoxins with potent anti-HIV activity from Alternaria tenuissima QUE1Se, a fungal endophyte of Quercus emoryiBioorg. Med. Chem.22(21),6112-6116(2014)

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