3-Isomangostin
Cat. No.：YN483397
CAS No. ：19275-46-8
| 产品名称: | 3-Isomangostin |
| CAS No.: | 19275-46-8 |
| Chemical Name: | 3,4-dihydro-5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-butenyl)-2H,6H-pyrano[3,2-b]xanthen-6-one |
| Synonyms: | 3-异倒捻子素 |
| 分子量: | 410.46 |
| 分子式: | C₂₄H₂₆O₆ |
| SMILES: | C/C(C)=C\CC1=C2C(OC3=C(C(O)=C4C(OC(C)(C)CC4)=C3)C2=O)=CC(O)=C1OC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 3-Isomangostin 可从Garciniamangostana.L.壳中提取，3-Isomangostin 是一种有效的 MutT 同系物 1 (MTH1) 抑制剂，IC50值为 52 nM。3-Isomangostin 可用于进行开发抗癌剂。 |
| IC50和靶点: | |
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Khaw, K.Y., Choi, S.B., Tan, S.C., et al.Prenylated xanthones from mangosteen as promising cholinesterase inhibitors and their molecular docking studiesPhytomedicine21(11),1303-1309(2014)
Fatmawati, S., Ersam, T., and Shimizu, K.The inhibitory activity of aldose reductase in vitro by constituents of Garcinia mangostana LinnPhytomedicine22(1),49-51(2015)
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Vemu, B., Nauman, M.C., Veenstra, J.P., et al.Structure activity relationship of xanthones for inhibition of cyclin dependent kinase 4 from mangosteen (Garcinia mangostana L.)Int. J. Nutr.4(2),38-45(2019)
Nauman, M.C., Tocmo, R., Vemu, B., et al.Inhibition of CDK2/CyclinE1 by xanthones from the mangosteen (Garcinia mangostana): A structure-activity relationship studyNat. Prod. Res.35(23),5429-5433(2021)
