Mitraphylline
Cat. No.：YN483456
CAS No. ：509-80-8
| 产品名称: | Mitraphylline |
| CAS No.: | 509-80-8 |
| Chemical Name: | (1'S,3R,4'aS,5'aS,10'aR)-1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, methyl ester |
| Synonyms: | 帽柱叶碱 |
| 分子量: | 368.43 |
| 分子式: | C₂₁H₂₄N₂O₄ |
| SMILES: | O=C1NC2=C([C@@]13CCN4C[C@@]5([C@@H](OC=C([C@]5(C[C@]43[H])[H])C(OC)=O)C)[H])C=CC=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Mitraphylline 是绒毛钩藤中主要的五环吲哚类生物碱。Mitraphylline 能抑制脂多糖介导的原代人中性粒细胞活化。 |
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Montserrat-de la Paz, S., Fernandez-Arche, A., de la Puerta, R., et al.Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophilsPhytomedicine23(2),141-148(2016)
García Prado, E., García Gimenez, M.D., De La Puerta Vázquez, R., et al.Antiproliferative effects of mitraphylline, a pentacyclic oxindole alkaloid of Uncaria tomentosa on human glioma and neuroblastoma cell linesPhytomedicine14(4),280-284(2007)
García Giménez, D., García Prado, E., Sáenz Rodríguez, T., et al.Cytotoxic effect of the pentacyclic oxindole alkaloid mitraphylline isolated from Uncaria tomentosa bark on human Ewing's sarcoma and breast cancer cell linesPlanta Med.76(2),133-136(2010)
Rojas-Duran, R., González-Aspajo, G., Ruiz-Martel, C., et al.Anti-inflammatory activity of mitraphylline isolated from Uncaria tomentosa barkJ. Ethnopharmacol.143(3),801-804(2012)
