GPRP acetate
Cat. No.：YN483745
CAS No. ：157009-81-9
规格
价格(RMB)
库存
| 产品名称: | GPRP acetate |
| CAS No.: | 157009-81-9 |
| Chemical Name: | glycyl-L-prolyl-L-arginyl-L-proline, monoacetate |
| Synonyms: | Gly-Pro-Arg-Pro acetate; Pefa 6003 acetate |
| 分子量: | 485.53 |
| 分子式: | C₂₀H₃₅N₇O₇ |
| SMILES: | O=C(N1CCC[C@H]1C(O)=O)[C@H](CCCNC(N)=N)NC([C@@H]2CCCN2C(CN)=O)=O.OC(C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GPRP acetate (Gly-Pro-Arg-Pro acetate) 是一种纤维蛋白聚合抑制剂, 能够抑制纤维蛋白原与血小板膜糖蛋白 Ⅱb/IIIa 复合物(糖蛋白 IIb/IIIa 受体)之间的相互作用。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Laudano, A.P., and Doolittle, R.F.Synthetic peptide derivatives that bind to fibrinogen and prevent the polymerization of fibrin monomersProc. Natl. Acad. Sci. USA75(7),3085-3089(1978)
Plow, E.F., and Marguerie, G.Inhibition of fibrinogen binding to human platelets by the tetrapeptide glycyl-L-prolyl-L-arginyl-L-prolineProc. Natl. Acad. Sci. USA79(12),3711-3715(1982)
Adelman, B., Gennings, C., Stony, J., et al.Synergistic inhibition of platelet aggregation by fibrinogen-related peptidesCirc. Res.67(4),941-947(1990)
