Thymalfasin
Cat. No.:YN483749
产品名称: | Thymalfasin |
CAS No.: | 62304-98-7 |
Chemical Name: | |
Synonyms: | 胸腺法新; Thymosin α1 |
分子量: | 3108.28 |
分子式: | C₁₂₉H₂₁₅N₃₃O₅₅ |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Thymalfasin (thymosin-alpha 1) 是一个免疫调节化合物,能够提高 Thl 的免疫应答。 |
IC50和靶点: | |
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In Vivo: | |
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Manrow, R.E., Leone, A., Krug, M.S., et al.The human prothymosin α gene family contains several processed pseudogenes lacking deleterious lesionsGenomics13(2),319-331(1992)
Binsfeld, M., Hannon, M., Otjacques, E., et al.Impact of the immunomodulating peptide thymosin alpha 1 on multiple myeloma and immune recovery after hematopoietic stem cell transplantationCancer Immunol. Immunother.64(8),989-998(2015)
Bo, C., Wu, Q., Zhao, H., et al.Thymosin α1 suppresses migration and invasion of PD-L1 high-expressing non-small-cell lung cancer cells via inhibition of STAT3-MMP2 signalingOnco. Targets Ther.11,7255-7270(2018)
Romani, L., Oikonomou, V., Moretti, S., et al.Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosisNat. Med.23(5),590-600(2017)