Kisspeptin-10, human
Cat. No.:YN483781
产品名称: | Kisspeptin-10, human |
CAS No.: | 374675-21-5 |
Chemical Name: | L-tyrosyl-L-asparaginyl-L-tryptophyl-L-asparaginyl-L-seryl-L-phenylalanylglycyl-L-leucyl-L-arginyl-L-phenylalaninamide |
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分子量: | 1302.44 |
分子式: | C₆₃H₈₃N₁₇O₁₄ |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Kisspeptin-10, human 是一种有效的血管收缩剂和血管生成抑制剂。Kisspeptin-10, human 通过其受体 GPR54 来抑制肿瘤转移作用。Kisspeptin-10-GPR54 系统在胚胎肾脏发育中起重要作用。Kisspeptin-10/GPR54 信号通过 NFATc4 介导的 BMP2 表达来诱导成骨细胞分化。 |
IC50和靶点: | |
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Ohtaki, T., Shintani, Y., Honda, S., et al.Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptorNature411(6837),613-617(2001)
Tomita, K., Niida, A., Osishi, S., et al.Structure-activity relationship study on small peptidic GPR54 agonistsBioor. Med. Chem. Lett.14(22),7595-7603(2006)
Hori, A., Honda, S., Asada, M., et al.Metastin suppresses the motility and growth of CHO cells transfected with its receptorBiochem. Biophys. Res. Commun.286(5),958-963(2001)