Ac-DEVD-AFC
Cat. No.:YN483810
产品名称: | Ac-DEVD-AFC |
CAS No.: | 201608-14-2 |
Chemical Name: | N-acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine |
Synonyms: | |
分子量: | 729.61 |
分子式: | C₃₀H₃₄F₃N₅O₁₃ |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Ac-DEVD-AFC 是一种荧光底物 (λex=400 nm, λem=530 nm)。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Lazebnik, Y.A., Kaufmann, S.H., Desnoyers, S., et al.Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICENature371(6495),346-347(1994)
Xiang, J., Chao, D.T., and Korsmeyer, S.J.BAX-induced cell death may not require interleukin 1β-converting enzyme-like proteasesProc. Natl. Acad. Sci. USA93(25),14559-14563(1996)
Chandler, J.M., Cohen, G.M., and MacFarlane, M.Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liverJ. Biol. Chem.273(18),10815-10818(1998)
Marcelli, M., Cunningham, G.R., Haidacher, S.J., et al.Caspase-7 is activated during lovastatin-induced apoptosis of the prostate cancer cell line LNCaPCancer Res.58(1),76-83(1998)