Prolactin Releasing Peptide (1-31), human
Cat. No.:YN483904
CAS No. :215510-22-8
产品名称: | Prolactin Releasing Peptide (1-31), human |
CAS No.: | 215510-22-8 |
Chemical Name: | L-seryl-L-arginyl-L-threonyl-L-histidyl-L-arginyl-L-histidyl-L-seryl-L-methionyl-L-α-glutamyl-L-isoleucyl-L-arginyl-L-threonyl-L-prolyl-L-α-aspartyl-L-isoleucyl-L-asparaginyl-L-prolyl-L-alanyl-L-tryptophyl-L-tyrosyl-L-alanyl-L-seryl-L-arginylglycyl-L-isol |
Synonyms: | |
分子量: | 3664.15 |
分子式: | C₁₆₀H₂₅₂N₅₆O₄₂S |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Prolactin Releasing Peptide (1-31), human是高亲和力的GPR10配体,其引起催乳素的释放。人和大鼠Prolactin Releasing Peptide (1-31) 结合GPR10的Ki值分别为 1.03 和 0.33 nM。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
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Seal, L.G., Small, C.J., Shillo, W.S., et al.PRL-releasing peptide inhibits food intake in male rats via the dorsomedial hypothalamic nucleus and not the paraventricular hypothalamic nucleusEndocrinology142(10),4236-4243(2001)
Langmead, C.J., Szekeres, P.G., Chambers, J.K., et al.Characterization of the binding of [125I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptorBr. J. Pharmacol.131(4),683-688(2000)
Engström, M., Brandt, A., Wurster, S., et al.Prolactin releasing peptide has high affinity and efficacy at neuropeptide FF2 receptorsJ. Pharmacol. Exp. Ther.305(3),825-832(2003)
Seal, L.J., Small, C.J., Kim, M.S., et al.Prolactin releasing peptide (PrRP) stimulates luteinizing hormone (LH) and follicle stimulating hormone (FSH) via a hypothalamic mechanism in male ratsEndocrinology141(5),1909-1912(2000)