Cyclo(Phe-Pro)
Cat. No.：YN484041
CAS No. ：14705-60-3
| 产品名称: | Cyclo(Phe-Pro) |
| CAS No.: | 14705-60-3 |
| Chemical Name: | hexahydro-3-(phenylmethyl)-pyrrolo[1,2-a]pyrazine-1,4-dione |
| Synonyms: | Cyclo(phenylalanylprolyl); A-64863 |
| 分子量: | 244.29 |
| 分子式: | C₁₄H₁₆N₂O₂ |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)) 是一种创伤弧菌的群体感应分子，通过与 RIG-I 的特异性相互作用，抑制 RIG-I 的多泛素化，并抑制 IRF-3 的激活和 I 型干扰素的产生。Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)) 增强 HCV 和流感病毒的易感性。 |
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Bina, X.R., Taylor, D.L., Vikram, A., et al.Vibrio cholerae ToxR downregulates virulence factor production in response to cyclo(Phe-Pro)mBio4(5),e00366-00313(2013)
Lee, W., Lee, S.-H., Kim, M., et al.Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunityNat. Commun.9(1),1606(2018)
