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D-Mannoheptulose

Cat. No.:YN484290

  • CAS No. :3615-44-9

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: D-Mannoheptulose
      CAS No.: 3615-44-9
      Chemical Name: D-manno-2-heptulose
      Synonyms:
      分子量:210.18
      分子式:C₇H₁₄O₇
      SMILES:OCC([C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: D-Mannoheptulose 是鳄梨中一种主要的非结构性碳水化合物。D-Mannoheptulose 是D-glucose磷酸化的特异性抑制剂。D-Mannoheptulose 能阻塞大鼠胰岛素的释放和对碳水化合物的利用。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Coore, H.G., and Randle, P.J.Inhibition of glucose phosphorylation by mannoheptuloseBiochem. J.91(1),56-59(1964)

      Ashcroft, S.J.H., and Randle, P.J.Enzymes of glucose metabolism in normal mouse pancreatic isletsBiochem. J.119(1),5-15(1970)

      Dai, N., Schaffer, A., Petreikov, M., et al.Overexpression of Arabidopsis hexokinase in tomato plants inhibits growth, reduces photosynthesis, and induces rapid senescencePlant Cell11(7),1253-1266(1999)

      Ashcroft, S.J.H., Weerasinghe, L.C., and Randle, P.J.Interrelationship of islet metabolism, adenosine triphosphate content and insulin releaseBiochem. J.132(2),223-231(1973)

      Johnson, D., Shepherd, R.M., Gill, D., et al.Glucose-dependent modulation of insulin secretion and intracellular calcium ions by GKA50, a glucokinase activatorDiabetes56(6),1694-1702(2007)

      Li, M.V., Chen, W., Harmancey, R.N., et al.Glucose-6-phosphate mediates activation of the carbohydrate responsive binding protein (ChREBP)Biochem. Biophys. Res. Commun.395(3),395-400(2010)

      McKnight, L.L., Flickinger, E.A., France, J., et al.Mannoheptulose has differential effects on fasting and postprandial energy expenditure and respiratory quotient in adult Beagle dogs fed diets of different macronutrient contentsJ. Nutr. Sci.3,e17(2014)

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