4-Hydroxymephenytoin
Cat. No.：YN484321
CAS No. ：61837-65-8
| 产品名称: | 4-Hydroxymephenytoin |
| CAS No.: | 61837-65-8 |
| Chemical Name: | 5-ethyl-5-(4-hydroxyphenyl)-3-methyl-2,4-imidazolidinedione |
| Synonyms: | 羟基香豆素 |
| 分子量: | 234.25 |
| 分子式: | C₁₂H₁₄N₂O₃ |
| SMILES: | O=C1N(C)C(C(C2=CC=C(O)C=C2)(CC)N1)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 4-Hydroxymephenytoin 是抗癫痫药 mephenytoin 的代谢物; mephenytoin 为 CYP2C19 的一种配体。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Stewart, N.A., Buch, S.C., Conrads, T.P., et al.A UPLC-MS/MS assay of the "Pittsburgh cocktail": Six CYP probe-drug/metabolites from human plasma and urine using stable isotope dilutionAnalyst136(3),605-612(2011)
Jansson, B., Simonsson, U.S.H., and Ashton, M.Simultaneous enantiospecific separation and quantitation of mephenytoin and its metabolites nirvanol and 4'-hydroxymephenytoin in human plasma by liquid chromatographyJ. Chromatogr. B Analyt. Technol. Biomed. Life Sci.791(1-2),179-191(2003)
