Oxfenicine
Cat. No.：YN484415
CAS No. ：32462-30-9
| 产品名称: | Oxfenicine |
| CAS No.: | 32462-30-9 |
| Chemical Name: | αS-amino-4-hydroxy-benzeneacetic acid |
| Synonyms: | L-p-Hydroxyphenylglycine; 4-Hydroxy-L-phenylglycine; UK 25842 |
| 分子量: | 167.16 |
| 分子式: | C₈H₉NO₃ |
| SMILES: | O=C(O)[C@@H](N)C1=CC=C(O)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Oxfenicine (L-p-Hydroxyphenylglycine) 是一种具有口服活性的肉碱棕榈酰转移酶-1 抑制剂。Oxfenicine 可抑制心脏中脂肪酸的氧化。Oxfenicine 在缺血期间保护心脏免受坏死组织的损害。 |
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Barnish, I.T., Cross, P.E., Danilewicz, J.C., et al.Promotion of carbohydrate oxidation in the heart by some phenylglyoxylic acidsJ. Med. Chem.24(4),399-404(1981)
Bielefeld, D.R., Vary, T.C., and Neely, J.R.Inhibition of carnitine palmitoyl-CoA transferase activity and fatty acid oxidation by lactate and oxfenicine in cardiac muscleJ. Mol. Cell. Cardiol.17(6),619-625(1985)
Higgins, A.J., Morville, M., Burges, R.A., et al.Oxfenicine diverts rat muscle metabolism from fatty acid to carbohydrate oxidation and protects the ischaemic rat heartLife Sci.27(11),963-970(1980)
Burges, R.A., Gardiner, D.G., and Higgins, A.J.Protection of the ischaemic dog heart by oxfenicineLife Sci.29(18),1847-1853(1981)
