ULS 欢迎您!
ULS 欢迎您!
> 产品中心 > 抑制剂 & 激动剂 > Others > Others

Cyclosporin D

Cat. No.:YN484421

  • CAS No. :63775-96-2

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Cyclosporin D
      CAS No.: 63775-96-2
      Chemical Name: 7-L-valine-cyclosporin A
      Synonyms:
      分子量:1216.64
      分子式:C₆₃H₁₁₃N₁₁O₁₂
      SMILES:暂无
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Cyclosporin D 是 Cyclosporin A 的代谢产物,是一种弱免疫抑制剂。Cyclosporin D 作为 Cyclosporin A 定量的内标,Cyclosporin A 是一种免疫抑制药物,通过抑制钙调磷酸酶和钙调磷酸酶依赖性转录因子激活的T细胞核因子 (NFAc) 来抑制 T 细胞活化。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Jorgensen, K.A., Koefoed-Nielsen, P.B., and Karamperis, N.Calcineurin phosphatase activity and immunosuppression. A review on the role of calcineurin phosphatase activity and the immunosuppressive effect of cyclosporin A and tacrolimusScand. J. Immunol.57(2),93-98(2003)

      Vollenbroeker, B., Koch, J.H., Fobker, M., et al.Determination of cyclosporine and its metabolites in blood via HPLC-MS and correlation to clinically important parametersTransplant. Proc.37(4),1741-1744(2005)

      von Wartburg, A., and Traber, R.Cyclosporins, fungal metabolites with immunosuppressive activitiesProg. Med. Chem.25,1-33(1988)

      Copeland, K.R., Yatscoff, R.W., and McKenna, R.M.Immunosuppressive activity of cyclosporine metabolites compared and characterized by mass spectroscopy and nuclear magnetic resonanceClin. Chem.36(2),225-229(1990)

      Kaiser, P., Akerboom, T., Wood, W.G., et al.A new approach for the determination of immunosuppressive drugs using HPLC-MS/MS and Cs+ adductsGer. Med. Sci.4,1-12(2006)

    • 摩尔计算器
    • 稀释计算器
    摩尔浓度计算器方程 :
    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    计算

    质量 浓度 体积 分子量
    稀释计算器 :
    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
    • C1
      V1
      C2
      V2
    • 您最近查看的产品:
    相关产品


    ULS 的所有产品和服务仅用于科学研究,我们不为任何其他用途提供产品和服务(也不为任何个人提供产品和服务)Copyright © 2020-2021 ULS. All Rights Reserved. 备案号:粤ICP备2021013238号-1