Diroximel fumarate
Cat. No.：YN480057
CAS No. ：1577222-14-0
规格
价格(RMB)
库存
| 产品名称: | Diroximel fumarate |
| CAS No.: | 1577222-14-0 |
| Chemical Name: | (2E)-butenedioic acid, 1-[2-(2,5-dioxo-1-pyrrolidinyl)ethyl] 4-methyl ester |
| Synonyms: | ALKS 8700; BIIB098 |
| 分子量: | 255.22 |
| 分子式: | C₁₁H₁₃NO₆ |
| SMILES: | O=C(OCCN1C(CCC1=O)=O)/C=C/C(OC)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Diroximel fumarate (ALKS 8700) 是一种具有口服活性的富马酸单乙酯 (MMF) 的前体药物，为一种控释制剂。Diroximel fumarate 被认为与其活性代谢物富马酸二甲酯 (DMF) 的活性等效。Diroximel fumarate 具有良好的安全性和有效性，有用于多发性硬化 (MS) 研究的潜力。 |
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Naismith, R.T., Wolinsky, J.S., Wundes, A., et al.Diroximel fumarate (DRF) in patients with relapsing-remitting multiple sclerosis: Interim safety and efficacy results from the phase 3 EVOLVE-MS-1 studyMult. Scler.,(2019)
