Heparastatin
Cat. No.：YN480095
CAS No. ：153758-25-9
规格
价格(RMB)
库存
| 产品名称: | Heparastatin |
| CAS No.: | 153758-25-9 |
| Chemical Name: | 4S,5R-dihydroxy-6R-[(2,2,2-trifluoroacetyl)amino]-3S-piperidinecarboxylic acid |
| Synonyms: | |
| 分子量: | 272.18 |
| 分子式: | C₈H₁₁F₃N₂O₅ |
| SMILES: | O=C([C@H]1CN[C@H](NC(C(F)(F)F)=O)[C@@H](O)[C@H]1O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Heparastatin 是乙酰肝素酶 (heparanase) 的一个抑制剂。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Nishimura, Y., Shitara, E., Adachi, H., et al.Flexible synthesis and biological activity of uronic acid-type gem-diamine 1-N-iminosugars: A new family of glycosidase inhibitorsJ. Org. Chem.65(1),2-11(2000)
Sue, M., Higashi, N., Shida, H., et al.An iminosugar-based heparanase inhibitor heparastatin (SF4) suppresses infiltration of neutrophils and monocytes into inflamed dorsal air pouchesInt. Immunopharmacol.35,15-21(2016)
Nishimura, Y., Satoh, T., Kondo, S., et al.Effect on spontaneous metastasis of mouse Lewis lung carcinoma by a trifluoroacetamide analogue of siastatin BJ. Antibiot. (Tokyo)47(7),840-842(1994)
