NIH-12848
Cat. No.：YN480117
CAS No. ：959551-10-1
规格
价格(RMB)
库存
| 产品名称: | NIH-12848 |
| CAS No.: | 959551-10-1 |
| Chemical Name: | N-(2-thienylmethyl)-2-[2-(trifluoromethyl)phenyl]-4-quinazolinamine |
| Synonyms: | NIH12848,NIH 12848 |
| 分子量: | 385.41 |
| 分子式: | C₂₀H₁₄F₃N₃S |
| SMILES: | FC(C1=CC=CC=C1C2=NC(NCC3=CC=CS3)=C4C=CC=CC4=N2)(F)F |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | NIH-12848推定的磷脂酰肌醇5-磷酸4-激酶γ (PI5P4Kγ)，IC50值为1 μM。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Clarke, J.H., Giudici, M.L., Burke, J.E., et al.The function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) explored using a specific inhibitor that targets the PI5P-binding siteBiochem. J.466(2),359-367(2015)
Dexheimer, T.S., Rosenthal, A.S., Luci, D.K., et al.Synthesis and structure-activity relationship studies of N-benzyl-2-phenylpyrimidin-4-amine derivatives as potent USP1/UAF1 deubiquitinase inhibitors with anticancer activity against nonsmall cell lung cancerJ. Med. Chem.57(19),8099-8110(2014)
