Deferitrin
Cat. No.：YN480369
CAS No. ：239101-33-8
规格
价格(RMB)
库存
| 产品名称: | Deferitrin |
| CAS No.: | 239101-33-8 |
| Chemical Name: | (4S)-2-(2,4-dihydroxyphenyl)-4,5-dihydro-4-methyl-4-thiazolecarboxylic acid |
| Synonyms: | 地夫立群; GT-56-252 |
| 分子量: | 253.27 |
| 分子式: | C₁₁H₁₁NO₄S |
| SMILES: | O=C([C@]1(C)N=C(C2=CC=C(O)C=C2O)SC1)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Deferitrin (GT-56-252) 是一种去铁硫素 (DFT) 类似物，是一种具有口服活性的三叉戟铁螯合剂。Deferitrin 用于输血引起的慢性铁超负荷。Deferitrin 有用于严重的 β 地中海贫血的潜力。 |
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Bergeron, R.J., Wiegand, J., Bharti, N., et al.Desferrithiocin analogue iron chelators: Iron clearing efficiency, tissue distribution, and renal toxicityBiometals24(2),239-258(2011)
Bergeron, R.J., Wiegand, J., Weimar, W.R., et al.Comparison of iron chelator efficacy in iron-overloaded beagle dogs and monkeys (Cebus apella)Comp. Med.54(6),664-672(2004)
Bergeron, R.J., Wiegand, J., Weimar, W.R., et al.Iron chelation promoted by desazadesferrithiocin analogs: An enantioselective barrierChirality15(7),593-599(2003)
