PDD 00017273
Cat. No.：YN480384
CAS No. ：1945950-21-9
规格
价格(RMB)
库存
| 产品名称: | PDD 00017273 |
| CAS No.: | 1945950-21-9 |
| Chemical Name: | 1-[(1,3-dimethyl-1H-pyrazol-5-yl)methyl]-1,2,3,4-tetrahydro-N-(1-methylcyclopropyl)-3-[(2-methyl-5-thiazolyl)methyl]-2,4-dioxo-6-quinazolinesulfonamide |
| Synonyms: | PDD00017273 |
| 分子量: | 514.62 |
| 分子式: | C₂₃H₂₆N₆O₄S₂ |
| SMILES: | O=S(C1=CC2=C(N(CC3=CC(C)=NN3C)C(N(CC4=CN=C(C)S4)C2=O)=O)C=C1)(NC5(C)CC5)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PDD 00017273 是一种有效的聚(腺苷二磷酸核糖)水解酶 (PARG) 抑制剂，IC50值为 26 nM，KD值为 1.45 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
James, D.I., Smith, K.M., Jordan, A.M., et al.First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to OlaparibACS Chem Biol.11(11),3179-3190(2016)
