Ogerin
Cat. No.：YN480441
CAS No. ：1309198-71-7
规格
价格(RMB)
库存
| 产品名称: | Ogerin |
| CAS No.: | 1309198-71-7 |
| Chemical Name: | 2-[4-amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]-benzenemethanol |
| Synonyms: | |
| 分子量: | 307.35 |
| 分子式: | C₁₇H₁₇N₅O |
| SMILES: | OCC1=C(C2=NC(N)=NC(NCC3=CC=CC=C3)=N2)C=CC=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ogerin 是一种选择性的GPR68正向别构调节剂，pEC50值为 6.83。Ogerin 对 A2A受体具有适中的拮抗作用，Ki值为 220 nM；对 5-HT2B受体的拮抗作用较弱，Ki值为 736 nM。Ogerin 抑制小鼠对恐惧记忆的回忆。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Huang, X.-P., Karpiak, J., Kroeze, W.K., et al.Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65Nature527(7579),477-483(2015)
