PFM01
Cat. No.：YN480658
CAS No. ：1558598-41-6
规格
价格(RMB)
库存
| 产品名称: | PFM01 |
| CAS No.: | 1558598-41-6 |
| Chemical Name: | 5Z-[(4-hydroxyphenyl)methylene]-3-(2-methylpropyl)-2-thioxo-4-thiazolidinone |
| Synonyms: | |
| 分子量: | 293.40 |
| 分子式: | C₁₄H₁₅NO₂S₂ |
| SMILES: | O=C1N(CC(C)C)C(S/C1=C\C2=CC=C(O)C=C2)=S |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PFM01 是 N-烷基化的 Mirin 衍生物，是MRE11核酸内切酶抑制剂。PFM01 可以通过非同源末端连接 (NHEJ) 和同源重组 (HR) 调节双链断裂修复 (DSBR)。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Shibata, A., Moiani, D., Arvai, A.S., et al.DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activitiesMol. Cell53(1),7-18(2014)
