Barbadin
Cat. No.：YN480713
CAS No. ：356568-70-2
规格
价格(RMB)
库存
| 产品名称: | Barbadin |
| CAS No.: | 356568-70-2 |
| Chemical Name: | 3-Amino-5-[4-(phenylmethyl)phenyl]thieno[2,3-d]pyrimidin-4(3H)-one |
| Synonyms: | |
| 分子量: | 333.41 |
| 分子式: | C₁₉H₁₅N₃OS |
| SMILES: | O=C1C(C(C2=CC=C(CC3=CC=CC=C3)C=C2)=CS4)=C4N=CN1N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Barbadin 是一种选择性β-arrestin/β2-adaptin相互作用抑制剂，β-arrestin1和 β-arrestin2 的IC50值分别为 19.1 μM 和 15.6 μM。Barbadin 阻断激动剂促进 β2-adrenergic, V2-vasopressin 和 angiotensin-II type-1 受体的内吞作用。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Beautrait, A., et al.: Nat Commun. 8, 15054 (2017)
