MTSEA hydrobromide
Cat. No.:YN480721
产品名称: | MTSEA hydrobromide |
CAS No.: | 16599-33-0 |
Chemical Name: | S-(2-aminoethyl) ester methanesulfonothioic acid, monohydrobromide |
Synonyms: | |
分子量: | 236.15 |
分子式: | C₃H₁₀BrNO₂S₂ |
SMILES: | CS(=O)(SCCN)=O.Br |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | MTSEA hydrobromide 是一种巯基反应性化合物,可以修饰游离半胱氨酸残基,产生一个与赖氨酸大小相当的带正电荷侧链。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
O'Reilly, J.P., and Shockett, P.E.Time- and state-dependent effects of methanethiosulfonate ethylammonium (MTSEA) exposure differ between heart and skeletal muscle voltage-gated Na+ channelsBiochim. Biophys. Acta1818(3),443-447(2012)
Li, R.A., Tsushima, R.G., Kallen, R.G., et al.Pore residues critical for μ-CTX binding to rat skeletal muscle Na+ channels revealed by cysteine mutagenesisBiophys. J.73(4),1874-1884(1997)
Lang, R.J., Harvey, J.R., and Mulholland, E.L.Sodium (2-sulfonatoethyl) methanethiosulfonate prevents S-nitroso-L-cysteine activation of Ca2+-activated K+ (BKCa) channels in myocytes of the guinea-pig taenia caecaBr. J. Pharmacol.139(6),1153-1163(2003)