Ac-Ile-Glu-Thr-Asp-pNA
Cat. No.：YN480727
CAS No. ：219138-21-3
规格
价格(RMB)
库存
| 产品名称: | Ac-Ile-Glu-Thr-Asp-pNA |
| CAS No.: | 219138-21-3 |
| Chemical Name: | N-acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-N-(4-nitrophenyl)-L-α-asparagine |
| Synonyms: | Ac-IETD-pNA |
| 分子量: | 638.62 |
| 分子式: | C₂₇H₃₈N₆O₁₂ |
| SMILES: | O=C([C@@H](NC([C@H]([C@H](CC)C)NC(C)=O)=O)CCC(O)=O)N[C@H](C(N[C@H](C(NC1=CC=C(C=C1)[N+]([O-])=O)=O)CC(O)=O)=O)[C@@H](C)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ac-Ile-Glu-Thr-Asp-pNA 是 caspase-8 的底物。Caspase-8 结合并裂解Ile-Glu-Thr-Asp (IETD) 肽序列，释放对硝基苯胺，可通过 405 nm 处的比色检测来定量检测酶活性。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Smith, G.K., Barrett, D.G., Blackburn, K.J., et al.Expression, preparation, and high-throughput screening of caspase-8: Discovery of redox-based and steroid diacid inhibitionArch. Biochem. Biophys.399(2),195-205(2002)
