Fluorofenidone
Cat. No.:YN480738
| 产品名称: | Fluorofenidone |
| CAS No.: | 848353-85-5 |
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| Synonyms: | AKF-PD |
| 分子量: | 203.21 |
| 分子式: | C₁₂H₁₀FNO |
| SMILES: | O=C1C=CC(C)=CN1C2=CC=CC(F)=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Fluorofenidone (AKF-PD),AMR69 的类似物,具有同等的抗纤维化活性,但毒性低,半衰期长。Fluorofenidone (AKF-PD) 部分通过 PI3K/Akt 信号通路抑制 NADPH 氧化酶和细胞外基质 (ECM) 的沉积,从而减轻肾间质纤维化的发生。 |
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