Debutyldronedarone D6 hydrochloride
Cat. No.：YN480898
CAS No. ：1346598-70-6
规格
价格(RMB)
库存
| 产品名称: | Debutyldronedarone D6 hydrochloride |
| CAS No.: | 1346598-70-6 |
| Chemical Name: | N-(2-Butyl-3-(4-(3-(butylamino)propoxy-1,1,2,2,3,3-d6)benzoyl)benzofuran-5-yl)methanesulfonamide Hydrochloride; |
| Synonyms: | SR35021 D6 hydrochloride |
| 分子量: | 543.15 |
| 分子式: | C₂₇H₃₁D₆ClN₂O₅S |
| SMILES: | CS(=O)(NC1=CC=C(C2=C1)OC(CCCC)=C2C(C3=CC=C(C=C3)OC([2H])(C([2H])(C([2H])(NCCCC)[2H])[2H])[2H])=O)=O.Cl[H] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Debutyldronedarone D6 hydrochloride (SR35021 D6 hydrochloride) 是 Debutyldronedarone 的氘代物。Debutyldronedarone 是 Dronedarone (HY-A0016) 在人体中的主要循环活性代谢物 (metabolite)。Debutyldronedarone 的效力是Dronedarone 的1/10 到 1/3。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Singh, B., et al.: J. Cardiovas. Pharmacol., 52, 300 (2008)
Hoy, S., et al.: Drugs, 69, 1647 (2009)
Hohnloser, S., et al.: New Eng. J. Med., 360, 668 (2009)
