Iobenguane sulfate
Cat. No.:YN480970
产品名称: | Iobenguane sulfate |
CAS No.: | 87862-25-7 |
Chemical Name: | N-[(3-iodophenyl)methyl]-guanidine, hemisulfate |
Synonyms: | MIBG sulfate |
分子量: | 324.13 |
分子式: | C₈H₁₀IN₃.₁/₂H₂O₄S |
SMILES: | NC(NCC1=CC=CC(I)=C1)=N.O=S(O)(O)=O.[1/2] |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Iobenguane sulfate (MIBG sulfate) 是一种具有抗肿瘤活性的神经递质去甲肾上腺素的类似物。放射性碘代 Iobenguane sulfate 可用于肾上腺肿瘤诊断和肿瘤靶向药物的研究。Iobenguane sulfate 是一种高亲和力的霍乱毒素底物,干扰细胞单核(ADP-核糖基化)。 |
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Smets, L.A., Bout, B., and Wisse, J.Cytotoxic and antitumor effects of the norepinephrine analogue meta-iodo-benzylguanidine (MIBG)Cancer Chemother. Pharmacol.21(1),9-13(1988)
Loesberg, C., van Rooij, H., and Smets, L.A.Meta-iodobenzylguanidine (MIBG), a novel high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation)Biochim. Biophys. Acta1037(1),92-99(1990)