5-Hydroxymethyl-2’-deoxycytidine
Cat. No.：YN481075
CAS No. ：7226-77-9
规格
价格(RMB)
库存
| 产品名称: | 5-Hydroxymethyl-2’-deoxycytidine |
| CAS No.: | 7226-77-9 |
| Chemical Name: | 2'-deoxy-5-(hydroxymethyl)-cytidine |
| Synonyms: | 2'-脱氧-5-(羟甲基)胞啶; 5hmdC |
| 分子量: | 257.24 |
| 分子式: | C₁₀H₁₅N₃O₅ |
| SMILES: | OC[C@@H]1[C@H](C[C@H](N2C(N=C(C(CO)=C2)N)=O)O1)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 5-Hydroxymethyl-2’-deoxycytidine (5hmdC) 是 DNA 中 5-methyl-2'-deoxycytidine (5-mdC) 的氧化衍生物。5-Hydroxymethyl-2’-deoxycytidine 可能作为细胞不可逆转损伤的标志物。 |
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Song, C.X., Szulwach, K.E., Fu, Y., et al.Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosineNat. Biotechnol.29(1),68-72(2011)
Le, T., Kim, K.P., Fan, G., et al.A sensitive mass-spectrometry method for simultaneous quantification of DNA methylation and hydroxymethylation levels in biological samplesAnal. Biochem.412(2),203-209(2011)
Clark, T.A., Lu, X., Luong, K., et al.Enhanced 5-methylcytosine detection in single-molecule, real-time sequencing via Tet1 oxidationBMC Biol.11(4),1-10(2013)
Krais, A.M., Park, Y.J., Plass, C., et al.Determination of genomic 5-hydroxymethyl-2'-deoxycytidine in human DNA by capillary electrophoresis with laser induced fluorescenceEpigenetics6(5),560-565(2011)
