Droxidopa
Cat. No.：YN481182
CAS No. ：23651-95-8
规格
价格(RMB)
库存
| 产品名称: | Droxidopa |
| CAS No.: | 23651-95-8 |
| Chemical Name: | (βR),3-dihydroxy-L-tyrosine |
| Synonyms: | 屈昔多巴; L-DOPS; DOPS; SM5688 |
| 分子量: | 213.19 |
| 分子式: | C₉H₁₁NO₅ |
| SMILES: | OC1=C(O)C=CC([C@@H](O)[C@@H](C(O)=O)N)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Droxidopa (L-DOPS) 是 Droxidopa (w/w80%) 和 Pharmaceutical starch (w/w20%) 的混合物，可作为神经递质去甲肾上腺素和肾上腺素的原药，能透过血脑屏障。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Bartholini, G., Constantinidis, J., Puig, M., et al.The stereoisomers of 3,4-dihydroxyphenylserine as precursors of norepinephrineJ. Pharmacol. Exp. Ther.193(2),523-532(1975)
Coll, M., Rodriguez, S., Raurell, I., et al.Droxidopa, an oral norepinephrine precursor, improves hemodynamic and renal alterations of portal hypertensive ratsHepatology56(5),1849-1860(2012)
Kaufmann, H., Norcliffe-Kaufmann, L., and Palma, J.-A.Droxidopa in neurogenic orthostatic hypotensionExp. Rev. Cardiovasc. Ther.13(8),875-891(2015)
