Eliglustat hemitartrate
Cat. No.：YN481408
CAS No. ：928659-70-5
规格
价格(RMB)
库存
| 产品名称: | Eliglustat hemitartrate |
| CAS No.: | 928659-70-5 |
| Chemical Name: | N-[(1R,2R)-2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]-octanamide, 2R,3R-dihydroxybutanedioate (2:1) |
| Synonyms: | Genz-112638; Eliglustat tartrate |
| 分子量: | 959.17 |
| 分子式: | C₅₀H₇₈N₄O₁₄ |
| SMILES: | CCCCCCCC(N[C@H](CN1CCCC1)[C@@H](C2=CC=C(OCCO3)C3=C2)O)=O.CCCCCCCC(N[C@H](CN4CCCC4)[C@@H](C5=CC=C(OCCO6)C6=C5)O)=O.O=C(O)[C@H](O)[C@@H](O)C(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Eliglustat hemitartrate是高效特异，有口服活性的葡糖脑苷脂合成酶抑制剂，IC50值为24 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
McEachern, K.A., Fung, J., Komarnitsky, S., et al.A specific and potent inhibitor of glucosylceramide synthase for substrate inhibition therapy of Gaucher diseaseMol. Genet. Metab.91(3),259-267(2007)
