PCI-27483
Cat. No.:YN481541
产品名称: | PCI-27483 |
CAS No.: | 871266-63-6 |
Chemical Name: | N-[2-[5-[6-(aminoiminomethyl)-1H-benzimidazol-2-yl]-5'-(aminosulfonyl)-2',6-dihydroxy[1,1'-biphenyl]-3-yl]acetyl]-L-aspartic acid |
Synonyms: | PCI27483 |
分子量: | 596.57 |
分子式: | C₂₆H₂₄N₆O₉S |
SMILES: | O=C(O)C[C@@H](C(O)=O)NC(CC1=CC(C2=CC(S(=O)(N)=O)=CC=C2O)=C(O)C(C3=NC4=CC=C(C(N)=N)C=C4N3)=C1)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | PCI-27483 是FVIIa/tissue factor抑制剂,具有抗肿瘤的活性。 |
IC50和靶点: | |
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Solvent & Solubility: |
Gómez-Outes, A., Suárez-Gea, L., Lecumberri, R., et al.New parenteral anticoagulants in developmentTher. Adv. Cardiovasc. Disc.5(1),33-59(2011)
Prescott, J., Thiemann, P., and Loury, D.PCI-27483, a small molecule inhibitor of Factor VIIa, inhibits growth of BxPC3 pancreatic adenocarcinoma xenograft tumorsAACR Annual Meeting,(2008)