Acebilustat
Cat. No.：YN481611
CAS No. ：943764-99-6
规格
价格(RMB)
库存
| 产品名称: | Acebilustat |
| CAS No.: | 943764-99-6 |
| Chemical Name: | 4-[[(1S,4S)-5-[[4-[4-(2-oxazolyl)phenoxy]phenyl]methyl]-2,5-diazabicyclo[2.2.1]hept-2-yl]methyl]-benzoic acid |
| Synonyms: | 阿西鲁司特; CTX-4430 |
| 分子量: | 481.54 |
| 分子式: | C₂₉H₂₇N₃O₄ |
| SMILES: | O=C(O)C1=CC=C(CN2[C@](C3)([H])CN(CC4=CC=C(OC5=CC=C(C6=NC=CO6)C=C5)C=C4)[C@]3([H])C2)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Acebilustat (CTX-4430) 是一种可口服的白三烯 A4 水解酶抑制剂，用于炎症研究。 |
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Elborn, J.S., Horsley, A., MacGregor, G., et al.Phase I studies of acebilustat: Biomarker response and safety in patients with cystic fibrosisClin. Transl. Sci.10(1),28-34(2017)
Forrest, O.A., Ingersoll, S.A., Preininger, M.K., et al.Frontline Science: Pathological conditioning of human neutrophils recruited to the airway milieu in cystic fibrosisJ. Leukoc. Biol.104(4),665-675(2018)
