7-Epi 10-desacetyl paclitaxel
Cat. No.：YN481738
CAS No. ：78454-17-8
规格
价格(RMB)
库存
| 产品名称: | 7-Epi 10-desacetyl paclitaxel |
| CAS No.: | 78454-17-8 |
| Chemical Name: | (αR,βS)-β-(benzoylamino)-α-hydroxy-benzenepropanoic acid, (2aR,4R,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1 |
| Synonyms: | 7-epi-10-deacetyltaxol; 10-Deacetyl-7-epipaclitaxel |
| 分子量: | 811.87 |
| 分子式: | C₄₅H₄₉NO₁₃ |
| SMILES: | O=C(N[C@@H](C1=CC=CC=C1)[C@@H](O)C(O[C@H]2C[C@@](O)([C@@H](OC(C3=CC=CC=C3)=O)[C@@]4([H])[C@@]5(C)[C@H](O)C[C@]6([H])[C@@]4(OC(C)=O)CO6)C(C)(C)C([C@@H](O)C5=O)=C2C)=O)C7=CC=CC=C7 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 7-Epi 10-desacetyl paclitaxel (7-epi-10-deacetyltaxol) 是一种紫杉醇衍生物，对 HeLa 细胞具有细胞毒性，其 IC50值为 85 μM。 |
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Dang, P.H., Nguyen, H.X., Duong, T.T.T., et al.α-glucosidase inhibitory and cytotoxic taxane diterpenoids from the stem bark of Taxus wallichianaJ. Nat. Prod.80(4),1087-1095(2017)
Subban, K., Singh, S., Subramani, R., et al.Fungal 7-epi-10-deacetyltaxol produced by an endophytic Pestalotiopsis microspora induces apoptosis in human hepatocellular carcinoma cell line (HepG2)BMC Complement. Altern. Med.17(1),504(2017)
