Benserazide hydrochloride
Cat. No.：YN481811
CAS No. ：14919-77-8
规格
价格(RMB)
库存
| 产品名称: | Benserazide hydrochloride |
| CAS No.: | 14919-77-8 |
| Chemical Name: | 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide-serine, monohydrochloride |
| Synonyms: | 盐酸苄丝肼; Serazide; Ro 4-4602 |
| 分子量: | 293.70 |
| 分子式: | C₁₀H₁₆ClN₃O₅ |
| SMILES: | NC(CO)C(NNCC1=CC=C(O)C(O)=C1O)=O.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Benserazide hydrochloride (Serazide) 常用于帕金森病，是一种芳香族 L-氨基酸脱羧酶（AADC）的抑制剂。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Schultz, E.L-dopa as substrate for human duodenal catechol-O-methyltransferase and aromatic L-amino acid decarboxylaseBiomed. Chromatogr.4(6),242-244(1990)
Bender, D.A.Inhibition in vitro of the enzymes of the oxidative pathway of tryptophan metabolism and of nicotinamide nucleotide synthesis by benserazide, carbidopa and isoniazidBiochem. Pharmacol.29(5),707-712(1980)
Li, W., Zheng, M., Wu, S., et al.Benserazide, a dopadecarboxylase inhibitor, suppresses tumor growth by targeting hexokinase 2J. Exp. Clin. Cancer Res.36(1),58(2017)
Shen, H., Kannari, K., Yamato, H., et al.Effects of benserazide on L-DOPA-derived extracellular dopamine levels and aromatic L-amino acid decarboxylase activity in the striatum of 6-hydroxydopamine-lesioned ratsTohoku J. Exp. Med.199(3),149-159(2003)
