Moguisteine
Cat. No.:YN481821
| 产品名称: | Moguisteine | 
| CAS No.: | 119637-67-1 | 
| Chemical Name: | 2-[(2-methoxyphenoxy)methyl]-β-oxo-3-thiazolidinepropanoic acid, ethyl ester | 
| Synonyms: | 莫吉司坦; BBR-2173 | 
| 分子量: | 339.41 | 
| 分子式: | C₁₆H₂₁NO₅S | 
| SMILES: | COC1=CC=CC=C1OCC2N(C(CC(OCC)=O)=O)CCS2 | 
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. | 
| 运输: | Room temperature in continental US; may vary elsewhere. | 
| 产品描述: | Moguisteine(BBR-2173)是新型外周非麻醉性止咳化合物。 | 
| IC50和靶点: | |
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Gandolfi, C.A., Di Domenico, R., Spinelli, S., et al.N-acyl-2-substituted-1,3-thiazolidines, a new class of non-narcotic antitussive agents: Studies leading to the discovery of ethyl 2-[(2-methoxyphenoxy)methyl]-beta-oxothiazolidine-3-propanoateJ. Med. Chem.38(3),508-525(1995)
Ishii, R., Furuta, M., Hashimoto, M., et al.Effects of moguisteine on the cough reflex induced by afferent electrical stimulation of the superior laryngeal nerve in guinea pigsEur. J. Pharmacol.362(2-3),207-212(1998)
Gallico, L., Oggioni, N., Dalla Rosa, C., et al.Effects of moguisteine, a peripheral nonnarcotic antitussive agent, on airway inflammation in guinea-pigs in vivoEur. Respir. J.9(3),478-485(1996)