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Moguisteine

Cat. No.:YN481821

  • CAS No. :119637-67-1

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    • 产品名称: Moguisteine
      CAS No.: 119637-67-1
      Chemical Name: 2-[(2-methoxyphenoxy)methyl]-β-oxo-3-thiazolidinepropanoic acid, ethyl ester
      Synonyms:莫吉司坦; BBR-2173
      分子量:339.41
      分子式:C₁₆H₂₁NO₅S
      SMILES:COC1=CC=CC=C1OCC2N(C(CC(OCC)=O)=O)CCS2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Moguisteine(BBR-2173)是新型外周非麻醉性止咳化合物。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Gandolfi, C.A., Di Domenico, R., Spinelli, S., et al.N-acyl-2-substituted-1,3-thiazolidines, a new class of non-narcotic antitussive agents: Studies leading to the discovery of ethyl 2-[(2-methoxyphenoxy)methyl]-beta-oxothiazolidine-3-propanoateJ. Med. Chem.38(3),508-525(1995)

      Ishii, R., Furuta, M., Hashimoto, M., et al.Effects of moguisteine on the cough reflex induced by afferent electrical stimulation of the superior laryngeal nerve in guinea pigsEur. J. Pharmacol.362(2-3),207-212(1998)

      Gallico, L., Oggioni, N., Dalla Rosa, C., et al.Effects of moguisteine, a peripheral nonnarcotic antitussive agent, on airway inflammation in guinea-pigs in vivoEur. Respir. J.9(3),478-485(1996)

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