Dexrazoxane
Cat. No.:YN481835
| 产品名称: | Dexrazoxane | 
| CAS No.: | 24584-09-6 | 
| Chemical Name: | 4,4'-[(1S)-1-methyl-1,2-ethanediyl]bis-2,6-piperazinedione | 
| Synonyms: | 右雷佐生; ICRF-187; ADR-529; NSC-169780 | 
| 分子量: | 268.27 | 
| 分子式: | C₁₁H₁₆N₄O₄ | 
| SMILES: | C[C@H](N(C1)CC(NC1=O)=O)CN(C2)CC(NC2=O)=O | 
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. | 
| 运输: | Room temperature in continental US; may vary elsewhere. | 
| 产品描述: | Dexrazoxane (ICRF-187) 是心脏保护剂。 | 
| IC50和靶点: | |
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Yan, T., Deng, S., Metzger, A., et al.Topoisomerase IIα-dependent and -independent apoptotic effects of dexrazoxane and doxorubicinMol. Cancer Ther.8(5),1075-1085(2009)
Kurz, T., Grant, D., Andersson, R.G.G., et al.Effects of MnDPDP and ICRF-187 on doxorubicin-induced cardiotoxicity and anticancer activityTransl. Oncol.5(4),252-259(2012)
Junjing, Z., Yan, Z., and Baolu, Z.Scavenging effects of dexrazoxane on free radicalsJ. Clin. Biochem. Nutr.47(3),238-245(2010)