Flumethasone

Cat. No.：YN481950

CAS No. ：2135-17-3

产品名称:	Flumethasone
CAS No.:	2135-17-3
Chemical Name:	6α,9-difluoro-11β,17,21-trihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione
Synonyms:	氟米松; Flumetasone
分子量:	410.45
分子式:	C₂₂H₂₈F₂O₅
SMILES:	C[C@@]12[C@](C(CO)=O)(O)[C@H](C)C[C@@]1([H])[C@]3([H])C[C@H](F)C4=CC(C=C[C@]4(C)[C@@]3(F)[C@@H](O)C2)=O
存储:	Please store the product under the recommended conditions in theCertificate of Analysis.
运输:	Room temperature in continental US; may vary elsewhere.

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Purity: 98%

产品描述:	Flumethasone 是一种皮质类固醇，是一种局部用药，与 Clioquinol 联用于外耳炎和耳真菌病的研究, Flumethasone 作用于动物模型时, 抗炎活性比 Cortisone 高 420 倍。
IC50和靶点:
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Grossmann, C., Scholz, T., Rochel, M., et al.Transactivation via the human glucocorticoid and mineralocorticoid receptor by therapeutically used steroids in CV-1 cells: A comparison of their glucocorticoid and mineralocorticoid propertiesEur. J. Endocrinol.151(3),397-406(2004)
Ishiguro, H., Kawahara, T., Zheng, Y., et al.Differential regulation of bladder cancer growth by various glucocorticoids: Corticosterone and prednisone inhibit cell invasion without promoting cell proliferation or reducing cisplatin cytotoxicityCancer Chemother. Pharmacol.74(2),249-255(2014)
Bednarek, D., Szuster-Ciesielska, A., Zdzisiñska, B., et al.The effect of steroidal and non-steroidal anti-inflammatory drugs on the cellular immunity of calves with experimentally-induced local lung inflammationVet. Immunol. Immunopathol.71(1),1-15(1999)
de Preux Charles, A.-S., Bise, T., Baier, F., et al.Distinct effects of inflammation on preconditioning and regeneration of the adult zebrafish heartOpen Biol.6(7),(2016)