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FRAX486

Cat. No.：1232030-35-1

  • CAS No. ：1232030-35-1

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    • 产品名称: FRAX486
      CAS No.: 1232030-35-1
      Chemical Name:
      Synonyms:FRAX597;6-(2,4-Dichlorophenyl)-8-ethyl-2-{[3-fluoro-4-(1-piperazinyl)phen yl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one;FRAX 486;FRAX-486;Pyrido[2,3-d]pyriMidin-7(8H)-one, 6-(2,4-dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]aMino]-;6-(2,4-Dich
      分子量:513.39
      分子式:C₂₅H₂₃Cl₂FN₆O
      SMILES:FC1=CC(NC2=NC=C3C(N(CC)C(C(C4=CC=C(Cl)C=C4Cl)=C3)=O)=N2)=CC=C1N5CCNCC5
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Dolan, B.M., Duron, S.G., Campbell, D.A., et al.Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486Proc. Natl. Acad. Sci. USA110(14),5671-5676(2013)', 'Hayashi-Takagi, A., Araki, Y., Nakamura, M., et al.PAKs inhibitors ameliorate schizophrenia-associated dendritic spine deterioration in vitro and in vivo during late adolescenceProc. Natl. Acad. Sci. USA111(17),6461-6466(2014)
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