AZD 6482
Cat. No.：YN420038
CAS No. ：1173900-33-8
规格
价格(RMB)
库存
| 产品名称: | AZD 6482 |
| CAS No.: | 1173900-33-8 |
| Chemical Name: | 2-[[(1R)-1-[7-methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]-benzoic acid |
| Synonyms: | KIN-193 |
| 分子量: | 408.45 |
| 分子式: | C₂₂H₂₄N₄O₄ |
| SMILES: | O=C1N2C(C([C@H](NC3=CC=CC=C3C(O)=O)C)=CC(C)=C2)=NC(N4CCOCC4)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AZD 6482 (KIN-193) 是一种有效的选择性p110β抑制剂，IC50为 0.69 nM。 |
| IC50和靶点: | [{name:"PI3Kα:136 nM (IC50)"},{name: "PI3Kβ:0.69 nM (IC50)"},{name: "PI3Kδ:13.6 nM (IC50)"},{name: "PI3Kγ:47.8 nM (IC50)"},{name: "PI3K-C2β:54.1 nM (IC50)"},{name: "hVps34:3390 nM (IC50)"},{name: "DNA-PK:53.7 nM (IC50)"},{name: "PI4Kα:8830 nM (IC50)"},{name: "mTOR:3930 nM (IC50)'}, 'Autophagy'] |
| In Vitro: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
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