ON 146040
Cat. No.：YN420122
CAS No. ：1404231-34-0
规格
价格(RMB)
库存
| 产品名称: | ON 146040 |
| CAS No.: | 1404231-34-0 |
| Chemical Name: | |
| Synonyms: | ZINC211117138 |
| 分子量: | 489.55 |
| 分子式: | C₂₄H₂₃N₇O₃S |
| SMILES: | CN(CC1)CCN1C(C=C2)=CC=C2NC3=NC(S/C(C(N4)=O)=C\C5=CC=C([N+]([O-])=O)C=C5)=C4C=N3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ON 146040 是一种有效的PI3Kα和PI3Kδ抑制剂，IC50分别约为 14 和 20 nM。ON 146040 也抑制Abl1(IC50<150 nM)。 |
| IC50和靶点: | [{name:"PI3Kα:14 nM (IC50)"},{name: "PI3Kδ:20 nM (IC50)"},{name: "PI3Kγ:1 μM (IC50)"},{name: "PI3Kβ:3 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
