AS-252424
Cat. No.：YN420171
CAS No. ：900515-16-4
规格
价格(RMB)
库存
| 产品名称: | AS-252424 |
| CAS No.: | 900515-16-4 |
| Chemical Name: | 5-[5-(4-fluoro-2-hydroxy-phenyl)-furan-2-ylmethylene]-thiazolidine-2,4-dione |
| Synonyms: | AS252424,AS 252424 |
| 分子量: | 305.28 |
| 分子式: | C₁₄H₈FNO₄S |
| SMILES: | O=C(NC/1=O)SC1=C/C2=CC=C(C3=CC=C(F)C=C3O)O2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AS-252424 是一种有效的选择性PI3Kγ抑制剂，IC50为 30±10 nM。 |
| IC50和靶点: | [{name:"PI3Kα:935 nM (IC50)"},{name: "PI3Kγ:30 nM (IC50)"},{name: "PI3Kδ:20 μM (IC50)"},{name: "PI3Kβ:20 μM (IC50)"}] |
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| Clinical Trial: | |
| Solvent & Solubility: |
Pomel, V., Klicic, J., Covini, D., et al.Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase γJ. Med. Chem.49(13),3857-3871(2006)
