CID 2011756
Cat. No.：YN270229
CAS No. ：638156-11-3
| 产品名称: | CID 2011756 |
| CAS No.: | 638156-11-3 |
| Chemical Name: | 5-(3-chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-2-furancarboxamide |
| Synonyms: | CID-2011756,CID2011756 |
| 分子量: | 396.87 |
| 分子式: | C₂₂H₂₁ClN₂O₃ |
| SMILES: | O=C(C1=CC=C(C2=CC=CC(Cl)=C2)O1)NC3=CC=C(CN4CCOCC4)C=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CID 2011756 是一种广谱的，ATP 竞争性的PKD抑制剂，对 PKD1 的IC50值为 3.2 µM，在细胞中对 PKD2 和 PKD3 的IC50值分别为 0.6 和 0.7 µM；CID 2011756 同时具有抗肿瘤活性。 |
| IC50和靶点: | [{name:"Cellular PKD2:0.6 μM (IC50)"},{name: "Cellular PKD3:0.7 μM (IC50)"},{name: "PKD1:3.2 μM (IC50)"}] |
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| Solvent & Solubility: |
Rozengurt, E., Rey, O., and Waldron, R.T.Protein kinase D signalingJ. Biol. Chem.280(14),13205-13208(2005)
Sharlow, E.R., Mustata Wilson, G., Close, D., et al.Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activityPLoS One6(10),e25134(2011)
