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BMS-687453

Cat. No.：1000998-59-3

  • CAS No. ：1000998-59-3

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    • 产品名称: BMS-687453
      CAS No.: 1000998-59-3
      Chemical Name:
      Synonyms:(S)-4-(6-chloro-4-cyclopropyl-2-oxo-3-(2,2,2-trifluoroethyl)-1,2,3,4-tetrahydroquinazolin-4-yl)benzonitrile;2-[[3-[[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methoxy]phenyl]methyl-methoxycarbonylamino]acetic acid;BMS 687453;BMS-687453;7HA;AGN-PC-014V8R;
      分子量:444.86
      分子式:C₂₂H₂₁ClN₂O₆
      SMILES:ClC(C=C1)=CC=C1C2=NC(COC3=CC=CC(CN(C(OC)=O)CC(O)=O)=C3)=C(C)O2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Li, J., Kennedy, L.J., Shi, Y., et al.Discovery of an oxybenzylglycine based peroxisome proliferator activated receptor α selective agonist 2-((3-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic acid (BMS-687453)J. Med. Chem.53(7),2854-2864(2010)', 'Mukherjee, R., Locke, K.T., Miao, B., et al.Novel peroxisome proliferator-activated receptor α agonists lower low-density lipoprotein and triglycerides, raise high-density lipoprotein, and synergistically increase cholesterol excretion with a liver X receptor agonistJ. Pharmacol. Exp. Ther.327(3),716-726(2008)
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