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GSK3787

Cat. No.：188591-46-0

  • CAS No. ：188591-46-0

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    • 产品名称: GSK3787
      CAS No.: 188591-46-0
      Chemical Name:
      Synonyms:GSK3787，GSK-3787，GSK 3787
      分子量:392.78
      分子式:C₁₅H₁₂ClF₃N₂O₃S
      SMILES:O=C(NCCS(=O)(C1=NC=C(C(F)(F)F)C=C1)=O)C2=CC=C(Cl)C=C2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 0.98
    • Michalik, L., Desvergne, B., and Wahli, W.Peroxisome-proliferator-activated receptors and cancers: Complex storiesNat. Rev. Cancer4(1),61-70(2004)', 'Girroir, E.E., Hollingshead, H.E., Billin, A.N., et al.Peroxisome proliferator-activated receptor-ß/δ (PPAR ß/δ) ligands inhibit growth of UACC903 and MCF7 human cancer cell linesToxicology243(1-2),236-243(2008)', 'Peters, J.M., Foreman, J.E., and Gonzalez, F.J.Dissecting the role of peroxisome proliferator-activated receptor-ß/δ (PPARß/δ) in colon, breast, and lung carcinogenesisCancer Metastasis Rev.30(3-4),619-640(2011)', 'Elikkottil, J., Kohli, D.R., and Gupta, K.Antitumor activity of a PPARδ antagonistCancer Biol. Ther.8(13),1262-1264(2009)', 'Shearer, B.G., Wiethe, R.W., Ashe, A., et al.Identification and characterization of 4-chloro-N-(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide (GSK3787), a selective and irreversible peroxisome proliferator-activated receptor δ (PPARδ) antagonistJ. Med. Chem.53(4),1857-1861(2010)', 'Palkar, P.S., Borland, M.G., Naruhn, S., et al.Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-β/δ antagonist GSK3787Mol. Pharmacol.78(3),419-430(2010)
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