SYN1143
Cat. No.：YN440376
CAS No. ：913376-84-8
规格
价格(RMB)
库存
| 产品名称: | SYN1143 |
| CAS No.: | 913376-84-8 |
| Chemical Name: | |
| Synonyms: | c-Met/RON Dual Kinase Inhibitor, RON-IN-1 |
| 分子量: | 556.58 |
| 分子式: | C₃₁H₂₉FN₄O₅ |
| SMILES: | O=C(C1=C(C)N(CC(C)(O)C)N(C2=CC=CC=C2)C1=O)NC3=CC=C(OC4=CC=NC5=CC(OC)=CC=C45)C(F)=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SYN1143 是一种有效和选择性的c-Met/RON的双重抑制剂，IC50值分别为 4 和 9 nM。SYN1143 对Lck，Tie2，Src和BTK的抑制活性较弱，IC50值为 160 至 710 nM。SYN1143 可用于癌症的研究。 |
| IC50和靶点: | [{name:"RON:9 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
